cAMP and Epac in the regulation of tissue fibrosis

Fibrosis, the result of excess deposition of extracellular matrix (ECM), in particular collagen, leads to scarring and loss of function in tissues that include the heart, lung, kidney and liver. The second messenger cAMP can inhibit the formation and extent of ECM during this late phase of inflammat...

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Detalhes bibliográficos
Main Authors: Insel, Paul A, Murray, Fiona, Yokoyama, Utako, Romano, Silvia, Yun, Hongruo, Brown, Loren, Snead, Aaron, Lu, David, Aroonsakool, Nakon
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Themed Section: Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417479/
https://ncbi.nlm.nih.gov/pubmed/22233238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01847.x
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