cAMP and Epac in the regulation of tissue fibrosis

Fibrosis, the result of excess deposition of extracellular matrix (ECM), in particular collagen, leads to scarring and loss of function in tissues that include the heart, lung, kidney and liver. The second messenger cAMP can inhibit the formation and extent of ECM during this late phase of inflammat...

Full description

Saved in:
Bibliographic Details
Main Authors: Insel, Paul A, Murray, Fiona, Yokoyama, Utako, Romano, Silvia, Yun, Hongruo, Brown, Loren, Snead, Aaron, Lu, David, Aroonsakool, Nakon
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Themed Section: Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417479/
https://ncbi.nlm.nih.gov/pubmed/22233238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01847.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items