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Cytotoxic T lymphocyte antigen-2 alpha induces apoptosis of murine T-lymphoma cells and cardiac fibroblasts and is regulated by cAMP/PKA

The mechanism of cAMP-promoted apoptosis is not well defined. In wild-type (WT) murine S49 lymphoma cells, cAMP promotes apoptosis in a protein kinase A (PKA)-dependent manner. We find that treatment of WT S49 cells with 8-CPT-cAMP prominently increases the expression (as determined by DNA microarra...

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書誌詳細
主要な著者: Zhang, Lingzhi, Yun, Hongruo, Murray, Fiona, Lu, Ruilin, Wang, Lin, Hook, Vivian, Insel, Paul A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148345/
https://ncbi.nlm.nih.gov/pubmed/21620962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.014
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