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Radixin Assembles cAMP Effectors Epac and PKA into a Functional cAMP Compartment: ROLE IN cAMP-DEPENDENT CELL PROLIFERATION

cAMP is an ubiquitous second messenger. Localized areas with high cAMP concentration, i.e. cAMP microdomains, provide an elegant mechanism to generate signaling specificity and transduction efficiency. However, the mechanisms underlying cAMP effector targeting into these compartments is still unclea...

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Autors principals: Hochbaum, Daniel, Barila, Guillermo, Ribeiro-Neto, Fernando, Altschuler, Daniel L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013045/
https://ncbi.nlm.nih.gov/pubmed/21047789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163816
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