The Ca(2+) channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA

The sperm-specific Ca(2+) channel CatSper (cation channel of sperm) controls the influx of Ca(2+) into the flagellum and, thereby, the swimming behavior of sperm. A hallmark of human CatSper is its polymodal activation by membrane voltage, intracellular pH, and oviductal hormones. Whether CatSper is...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Tao, Young, Samuel, Krenz, Henrike, Tüttelmann, Frank, Röpke, Albrecht, Krallmann, Claudia, Kliesch, Sabine, Zeng, Xu-Hui, Brenker, Christoph, Strünker, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504923/
https://ncbi.nlm.nih.gov/pubmed/32703901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013218
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