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The Ca(2+) channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA
The sperm-specific Ca(2+) channel CatSper (cation channel of sperm) controls the influx of Ca(2+) into the flagellum and, thereby, the swimming behavior of sperm. A hallmark of human CatSper is its polymodal activation by membrane voltage, intracellular pH, and oviductal hormones. Whether CatSper is...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7504923/ https://ncbi.nlm.nih.gov/pubmed/32703901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013218 |
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