The CatSper channel: a polymodal chemosensor in human sperm

The sperm-specific CatSper channel controls the intracellular Ca(2+) concentration ([Ca(2+)](i)) and, thereby, the swimming behaviour of sperm. In humans, CatSper is directly activated by progesterone and prostaglandins—female factors that stimulate Ca(2+) influx. Other factors including neurotransm...

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Main Authors: Brenker, Christoph, Goodwin, Normann, Weyand, Ingo, Kashikar, Nachiket D, Naruse, Masahiro, Krähling, Miriam, Müller, Astrid, Kaupp, U Benjamin, Strünker, Timo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321208/
https://ncbi.nlm.nih.gov/pubmed/22354039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.30
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