A novel cross‐species inhibitor to study the function of CatSper Ca(2+) channels in sperm

BACKGROUND AND PURPOSE: Sperm from many species share the sperm‐specific Ca(2+) channel CatSper that controls the intracellular Ca(2+) concentration and, thereby, the swimming behaviour. A growing body of evidence suggests that the mechanisms controlling the activity of CatSper and its role during f...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Rennhack, Andreas, Schiffer, Christian, Brenker, Christoph, Fridman, Dmitry, Nitao, Elis T, Cheng, Yi‐Min, Tamburrino, Lara, Balbach, Melanie, Stölting, Gabriel, Berger, Thomas K, Kierzek, Michelina, Alvarez, Luis, Wachten, Dagmar, Zeng, Xu‐Hui, Baldi, Elisabetta, Publicover, Stephen J, Benjamin Kaupp, U, Strünker, Timo
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031884/
https://ncbi.nlm.nih.gov/pubmed/29723408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14355
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