Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease

Cigarette smoke-induced release of pro-inflammatory cytokines including interleukin-8 (IL-8) from inflammatory as well as structural cells in the airways, including airway smooth muscle (ASM) cells, may contribute to the development of chronic obstructive pulmonary disease (COPD). Despite the wide u...

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Main Authors: Oldenburger, Anouk, Roscioni, Sara S., Jansen, Esther, Menzen, Mark H., Halayko, Andrew J., Timens, Wim, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283666/
https://ncbi.nlm.nih.gov/pubmed/22363678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031574
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