Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease

Cigarette smoke-induced release of pro-inflammatory cytokines including interleukin-8 (IL-8) from inflammatory as well as structural cells in the airways, including airway smooth muscle (ASM) cells, may contribute to the development of chronic obstructive pulmonary disease (COPD). Despite the wide u...

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Главные авторы: Oldenburger, Anouk, Roscioni, Sara S., Jansen, Esther, Menzen, Mark H., Halayko, Andrew J., Timens, Wim, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283666/
https://ncbi.nlm.nih.gov/pubmed/22363678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031574
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