Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease

Cigarette smoke-induced release of pro-inflammatory cytokines including interleukin-8 (IL-8) from inflammatory as well as structural cells in the airways, including airway smooth muscle (ASM) cells, may contribute to the development of chronic obstructive pulmonary disease (COPD). Despite the wide u...

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Main Authors: Oldenburger, Anouk, Roscioni, Sara S., Jansen, Esther, Menzen, Mark H., Halayko, Andrew J., Timens, Wim, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283666/
https://ncbi.nlm.nih.gov/pubmed/22363678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031574
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