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TPA-023 attenuates subchronic phencyclidine-induced declarative and reversal learning deficits via GABA(A) receptor agonist mechanism: possible therapeutic target for cognitive deficit in schizophrenia

GABAergic drugs are of interest for the treatment of anxiety, depression, bipolar disorder, pain, cognitive impairment associated with schizophrenia (CIAS), and other neuropsychiatric disorders. Some evidence suggests that TPA-023, (7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2...

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Dades bibliogràfiques
Publicat a:Neuropsychopharmacology
Autors principals: Rajagopal, Lakshmi, Huang, Mei, Michael, Eric, Kwon, Sunoh, Meltzer, Herbert Y.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180114/
https://ncbi.nlm.nih.gov/pubmed/30093697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0160-3
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