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A Role for Calmodulin-Stimulated Adenylyl Cyclases in Cocaine Sensitization

Cocaine sensitization is produced by repeated exposure to the drug and is thought to reflect neuroadaptations that contribute to addiction. Here, we identify the Ca(2+)/calmodulin-stimulated adenylyl cyclases, type 1 (AC1) and type 8 (AC8), as novel regulators of this behavioral plasticity. We show...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DiRocco, Derek P., Scheiner, Zachary S., Sindreu, Carlos Balet, Chan, Guy C.-K., Storm, Daniel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678191/
https://ncbi.nlm.nih.gov/pubmed/19244515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4356-08.2009
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