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A Role for Calmodulin-Stimulated Adenylyl Cyclases in Cocaine Sensitization

Cocaine sensitization is produced by repeated exposure to the drug and is thought to reflect neuroadaptations that contribute to addiction. Here, we identify the Ca(2+)/calmodulin-stimulated adenylyl cyclases, type 1 (AC1) and type 8 (AC8), as novel regulators of this behavioral plasticity. We show...

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Main Authors: DiRocco, Derek P., Scheiner, Zachary S., Sindreu, Carlos Balet, Chan, Guy C.-K., Storm, Daniel R.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678191/
https://ncbi.nlm.nih.gov/pubmed/19244515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4356-08.2009
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