A Role for Calmodulin-Stimulated Adenylyl Cyclases in Cocaine Sensitization

Cocaine sensitization is produced by repeated exposure to the drug and is thought to reflect neuroadaptations that contribute to addiction. Here, we identify the Ca(2+)/calmodulin-stimulated adenylyl cyclases, type 1 (AC1) and type 8 (AC8), as novel regulators of this behavioral plasticity. We show...

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Bibliographic Details
Main Authors: DiRocco, Derek P., Scheiner, Zachary S., Sindreu, Carlos Balet, Chan, Guy C.-K., Storm, Daniel R.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678191/
https://ncbi.nlm.nih.gov/pubmed/19244515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4356-08.2009
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