Resultados da pesquisa - ((((drug dev) OR (drug deal))) OR (drug de)) devel ther*

21

Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures [Corrigendum]

Por Mumoli L, Palleria C, Gasparini S, Citraro R, Labate A, Ferlazzo E, Gambardella A, De Sarro G, Russo E
Publicado em 2015-12-01

“...Drug Design, Development and Therapy...”
Obter o texto integral

Artigo

22

A carregar...

Multicomponent nanoparticles as nonviral vectors for the treatment of Fabry disease by gene therapy

Por Ruiz de Garibay, Aritz Pérez, Delgado, Diego, del Pozo-Rodríguez, Ana, Solinís, María Ángeles, Gascón, Alicia Rodríguez
Publicado em 2012

“... levels in FD with gene therapy....”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

23

A carregar...

Effect of renal impairment on the pharmacokinetics of prucalopride: a single- dose open-label Phase I study

Por Smith, William B, Mannaert, Erik, Verhaeghe, Tom, Kerstens, René, Vandeplassche, Lieve, Van de Velde, Vera
Publicado em 2012

Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

24

A carregar...

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis

Por Giacoppo, Sabrina, Soundara Rajan, Thangavelu, De Nicola, Gina Rosalinda, Iori, Renato, Bramanti, Placido, Mazzon, Emanuela
Publicado no Drug Des Devel Ther (2016)

“... new potential therapeutic target for MS treatment....”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

25

A carregar...

Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures

Por Mumoli, Laura, Palleria, Caterina, Gasparini, Sara, Citraro, Rita, Labate, Angelo, Ferlazzo, Edoardo, Gambardella, Antonio, De Sarro, Giovambattista, Russo, Emilio
Publicado no Drug Des Devel Ther (2015)

“... in the United States and the European Union as adjunctive therapy for patients with partial seizures...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

26

A carregar...

The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs

Por Serra, Raffaele, Gallelli, Luca, Conti, Angela, De Caridi, Giovanni, Massara, Mafalda, Spinelli, Francesco, Buffone, Gianluca, Caliò, Francesco Giuseppe, Amato, Bruno, Ceglia, Simona, Spaziano, Giuseppe, Scaramuzzino, Luca, Ferrarese, Alessia Giovanna, Grande, Raffaele, de Franciscis, Stefano
Publicado em 2014

“... (median age: 68.7 years) treated with standard treatment (compression therapy and surgery) + SDX (600...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

27

A carregar...

Women taking the “blue pill” (sildenafil citrate): such a big deal?

Por Lo Monte, Giuseppe, Graziano, Angela, Piva, Isabella, Marci, Roberto
Publicado no Drug Des Devel Ther (2014)

“... are still conflicting and the drug is not devoid of adverse effects. Furthermore, female sexual arousal...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

28

A carregar...

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Por da Silva, Cristiane França, Batista, Denise da Gama Jaén, de Araújo, Julianna Siciliano, Cunha-Junior, Edézio Ferreira, Stephens, Chad E, Banerjee, Moloy, Farahat, Abdelbasset A, Akay, Senol, Fisher, Mary K, Boykin, David W, Soeiro, Maria de Nazaré Correia
Publicado no Drug Des Devel Ther (2017)

“... EC(50) (drug concentration that reduces 50% of the number of the treated parasites) values ranging...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

29

A carregar...

Double-blind, randomized, double-dummy clinical trial comparing the efficacy of ketorolac trometamol and naproxen for acute low back pain

Por Plapler, Pérola Grinberg, Scheinberg, Morton Aaron, Ecclissato, Christina da Cunha, Bocchi de Oliveira, Monalisa Fernanda, Amazonas, Roberto Bleuel
Publicado no Drug Des Devel Ther (2016)

“...BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common type of medication...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

30

A carregar...

Bioequivalence of a biosimilar enoxaparin sodium to Clexane(®) after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers

Por Martínez González, Javier, Monreal, Mayte, Ayani Almagia, Ignacio, Llaudó Garín, Jordi, Ochoa Díaz de Monasterioguren, Lourdes, Gutierro Adúriz, Ibón
Publicado no Drug Des Devel Ther (2018)

“... enoxaparin to the reference drug, and to assess its safety and tolerability in healthy volunteers. PATIENTS...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

31

A carregar...

Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose

Por de la Torre-Iglesias, Paloma Marina, García-Rodriguez, Juan José, Torrado, Guillermo, Torrado, Susana, Torrado-Santiago, Santiago, Bolás-Fernández, Francisco
Publicado em 2014

“...BACKGROUND: Mebendazole (MBZ) is an extremely insoluble and therefore poorly absorbed drug...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

32

A carregar...

The impact of lipocalin-type-prostaglandin-D-synthase as a predictor of kidney disease in patients with type 2 diabetes

Por Bacci, Marcelo Rodrigues, Cavallari, Marina Romera, de Rozier-Alves, Ross Martin, Alves, Beatriz da Costa Aguiar, Fonseca, Fernando Luiz Affonso
Publicado no Drug Des Devel Ther (2015)

Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

33

A carregar...

Role of sodium tungstate as a potential antiplatelet agent

Por Fernández-Ruiz, Rebeca, Pino, Marc, Hurtado, Begoña, García de Frutos, Pablo, Caballo, Carolina, Escolar, Ginés, Gomis, Ramón, Diaz-Ricart, Maribel
Publicado no Drug Des Devel Ther (2015)

Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

34

A carregar...

Structure–activity exploration of a small-molecule Lipid II inhibitor

Por Fletcher, Steven, Yu, Wenbo, Huang, Jing, Kwasny, Steven M, Chauhan, Jay, Opperman, Timothy J, MacKerell, Alexander D, de Leeuw, Erik PH
Publicado no Drug Des Devel Ther (2015)

“... of BAS00127538 derivatives obtained by in silico analyses and de novo chemical synthesis. Our results...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

35

A carregar...

Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice

Por Yuan, Yong-Liang, Guo, Chang-Run, Cui, Ling-Ling, Ruan, Shi-Xia, Zhang, Chun-Feng, Ji, De, Yang, Zhong-Lin, Li, Fei
Publicado no Drug Des Devel Ther (2015)

“...BACKGROUND: Many synthesized drugs with clinical severe side effects have been used for diabetic...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

36

A carregar...

Involvement of poly(ADP-ribose) polymerase-1 in development of spinal cord injury in Chinese individuals: a Chinese clinical study

Por Meng, Qing-Tao, Yang, Guang, Li, Ren-Bo, Nie, Jing-Xin, Zhou, Wei, Yu, Hong-De, Chen, Bo, Jiang, Li, Shang, Jing-Bo
Publicado no Drug Des Devel Ther (2017)

Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

37

A carregar...

Prospective study on nanoparticle albumin-bound paclitaxel in advanced breast cancer: clinical results and biological observations in taxane-pretreated patients

Por Fabi, Alessandra, Giannarelli, Diana, Malaguti, Paola, Ferretti, Gianluigi, Vari, Sabrina, Papaldo, Paola, Nisticò, Cecilia, Caterino, Mauro, De Vita, Roy, Mottolese, Marcella, Iacorossi, Laura, Cognetti, Francesco
Publicado no Drug Des Devel Ther (2015)

“... drugs for the treatment of MBC, both in monotherapy and in combined schedules, but the need...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

38

A carregar...

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

Por De Sanctis, Rita, Marrari, Andrea, Marchetti, Silvia, Mussi, Chiara, Balzarini, Luca, Lutman, Fabio Romano, Daolio, Primo, Bastoni, Stefano, Bertuzzi, Alexia Francesca, Quagliuolo, Vittorio, Santoro, Armando
Publicado no Drug Des Devel Ther (2015)

“... therapeutic option for metastatic lipo- and leiomyosarcoma and suggests promise in synovial sarcomas and high...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

39

A carregar...

Pomalidomide in the treatment of multiple myeloma: design, development and place in therapy

Por Ríos-Tamayo, Rafael, Martín-García, Agustín, Alarcón-Payer, Carolina, Sánchez-Rodríguez, Dolores, de la Guardia, Ana María del Valle Díaz, García Collado, Carlos Gustavo, Jiménez Morales, Alberto, Jurado Chacón, Manuel, Cabeza Barrera, José
Publicado no Drug Des Devel Ther (2017)

“.... Immunomodulatory drugs play a key role in both the front-line and the relapsed/refractory setting. The combination...”
Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

40

A carregar...

Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis

Por Sato, Mariana R, Oshiro Junior, João A, Machado, Rachel TA, de Souza, Paula C, Campos, Débora L, Pavan, Fernando R, da Silva, Patricia B, Chorilli, Marlus
Publicado no Drug Des Devel Ther (2017)

Obter o texto integral
Obter o texto integral
Obter o texto integral

Artigo

Refinar a Pesquisa