Multicomponent nanoparticles as nonviral vectors for the treatment of Fabry disease by gene therapy

PURPOSE: Gene-mediated enzyme replacement is a reasonable and highly promising approach for the treatment of Fabry disease (FD). The objective of the present study was to demonstrate the potential applications of solid lipid nanoparticle (SLN)-based nonviral vectors for the treatment of FD. METHODS:...

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Hauptverfasser: Ruiz de Garibay, Aritz Pérez, Delgado, Diego, del Pozo-Rodríguez, Ana, Solinís, María Ángeles, Gascón, Alicia Rodríguez
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2012
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484727/
https://ncbi.nlm.nih.gov/pubmed/23118528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S36131
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