Effect of renal impairment on the pharmacokinetics of prucalopride: a single- dose open-label Phase I study

OBJECTIVE: To evaluate the pharmacokinetics of prucalopride in individuals with renal impairment (RI). METHODS: This open-label Phase I study (ClinicalTrials.gov identifier: NCT01674192) enrolled men and women aged 18–75 years who were classified by renal function: normal renal function (creatinine...

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Detalhes bibliográficos
Main Authors: Smith, William B, Mannaert, Erik, Verhaeghe, Tom, Kerstens, René, Vandeplassche, Lieve, Van de Velde, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529624/
https://ncbi.nlm.nih.gov/pubmed/23269861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S36142
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