THER-10. TELOMERE TARGETING BASED-THERAPIES TO TREAT THERAPY-RESISTANT PEDIATRIC BRAIN TUMORS

Por Sengupta, Satarupa, Kumar, Shiva Senthil, Mishra, Deepak, Drissi, Rachid
Publicado no Neuro Oncol (2019)

Schiff base derived from thiosemicarbazone and anthracene showed high potential in overcoming multidrug resistance in vitro with low drug resistance index

Por Bai, Jie, Wang, Rui-Hui, Qiao, Yan, Wang, Aidong, Fang, Chen-Jie
Publicado no Drug Des Devel Ther (2017)

Triazole derivatives with improved in vitro antifungal activity over azole drugs

Por Yu, Shichong, Chai, Xiaoyun, Wang, Yanwei, Cao, Yongbing, Zhang, Jun, Wu, Qiuye, Zhang, Dazhi, Jiang, Yuanying, Yan, Tianhua, Sun, Qingyan
Publicado em 2014

Milk derived colloid as a novel drug delivery carrier for breast cancer

Por Hayashi, Masamichi, Silanikove, Nissim, Chang, Xiaofei, Ravi, Rajani, Pham, Vui, Baia, Gilson, Paz, Keren, Brait, Mariana, Sidransky, David, Koch, Wayne M
Publicado no Cancer Biol Ther (2015)

Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug–Drug Interaction Between Clopidogrel and Dasabuvir

Por Shebley, M, Fu, W, Badri, P, Bow, DAJ, Fischer, V
Publicado no Clin Pharmacol Ther (2017)

Lipid-Based Nanoparticles as Pharmaceutical Drug Carriers: From Concepts to Clinic

Por Puri, Anu, Loomis, Kristin, Smith, Brandon, Lee, Jae-Ho, Yavlovich, Amichai, Heldman, Eli, Blumenthal, Robert
Publicado em 2009

Genetics-Based Pediatric Warfarin Dosage Regimen Derived Using Pharmacometric Bridging

Por Lala, Mallika, Burckart, Gilbert J., Takao, Cheryl M., Pravica, Vera, Momper, Jeremiah D., Gobburu, Jogarao V.S.
Publicado em 2013

Discovery of Novel Second Mitochondria-Derived Activator of Caspase Mimetics as Selective Inhibitor of Apoptosis Protein Inhibitors

Por Wang, Jin, Li, Wei
Publicado em 2014

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models

Por Tan, Cheau Yih, Lai, Ruenn Chai, Wong, Winnie, Dan, Yock Young, Lim, Sai-Kiang, Ho, Han Kiat
Publicado no Stem Cell Res Ther (2014)

Design, development, drug-likeness, and molecular docking studies of novel piperidin-4-imine derivatives as antitubercular agents

Por Revathi, Rajappan, Venkatesha Perumal, Ramachandran, Pai, Karkala Sreedhara Ranganath, Arunkumar, Govindakarnavar, Sriram, Dharmarajan, Kini, Suvarna Ganesh
Publicado no Drug Des Devel Ther (2015)

Multi-walled carbon nanotube-based systems for improving the controlled release of insoluble drug dipyridamole

Por Zhu, Wenquan, Huang, Haitao, Dong, Yan, Han, Cuiyan, Sui, Xiaoyu, Jian, Baiyu
Publicado no Exp Ther Med (2019)

Physiologically based and population PK modeling in optimizing drug development: A predict–learn–confirm analysis

Por Suri, A, Chapel, S, Lu, C, Venkatakrishnan, K
Publicado no Clin Pharmacol Ther (2015)

Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery...

Por Chow, Maggie Zi, Boheler, Kenneth R, Li, Ronald A
Publicado em 2013

Pediatric tuberculous meningitis: model-based approach to determining optimal doses of the anti-tuberculosis drugs rifampin and levofloxacin for children

Por Savic, Radojka M., Ruslami, Rovina, Hibma, Jennifer E., Hesseling, Anneke, Ramachandran, Geetha, Ganiem, A. Rizal, Swaminathan, Soumya, McIlleron, Helen, Gupta, Amita, Thakur, Kiran, van Crevel, Reinout, Aarnoutse, Rob, Dooley, Kelly E.
Publicado no Clin Pharmacol Ther (2015)

Afatinib treatment for her-2 amplified metastatic colorectal cancer based on patient-derived xenograft models and next generation sequencing

Por Yang, Mengyuan, Fang, Xuefeng, Li, Jun, Xu, Dong, Xiao, Qian, Yu, Shaojun, Hu, Hanguang, Weng, Shanshan, Ding, Kefeng, Yuan, Ying
Publicado no Cancer Biol Ther (2018)

Visual detection of glial cell line-derived neurotrophic factor based on a molecular translator and isothermal strand-displacement polymerization reaction

Por Zhang, Li-Yong, Xing, Tao, Du, Li-Xin, Li, Qing-Min, Liu, Wei-Dong, Wang, Ji-Yue, Cai, Jing
Publicado no Drug Des Devel Ther (2015)

Engineering human ventricular heart muscles based on a highly efficient system for purification...

Por Li, Bin, Yang, Hui, Wang, Xiaochen, Zhan, Yongkun, Sheng, Wei, Cai, Huanhuan, Xin, Haoyang, Liang, Qianqian, Zhou, Ping, Lu, Chao, Qian, Ruizhe, Chen, Sifeng, Yang, Pengyuan, Zhang, Jianyi, Shou, Weinian, Huang, Guoying, Liang, Ping, Sun, Ning
Publicado no Stem Cell Res Ther (2017)

Identification and Mechanistic Investigation of Drug–Drug Interactions Associated With Myopathy: A Translational Approach

Por Han, X, Quinney, SK, Wang, Z, Zhang, P, Duke, J, Desta, Z, Elmendorf, JS, Flockhart, DA, Li, L
Publicado no Clin Pharmacol Ther (2015)

Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source...

Por Babu, Tirumalasetty Muni Chandra, Rammohan, Aluru, Baki, Vijaya Bhaskar, Devi, Savita, Gunasekar, Duvvuru, Rajendra, Wudayagiri
Publicado no Drug Des Devel Ther (2016)

Edible bird’s nest attenuates procoagulation effects of high-fat diet in rats

Por Yida, Zhang, Imam, Mustapha Umar, Ismail, Maznah, Ismail, Norsharina, Hou, Zhiping
Publicado no Drug Des Devel Ther (2015)