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Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectives
Heart diseases remain a major cause of mortality and morbidity worldwide. However, terminally differentiated human adult cardiomyocytes (CMs) possess a very limited innate ability to regenerate. Directed differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854712/ https://ncbi.nlm.nih.gov/pubmed/23953772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt308 |
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