Triazole derivatives with improved in vitro antifungal activity over azole drugs

A series of triazole antifungal agents with piperidine side chains was designed and synthesized. The results of antifungal tests against eight human pathogenic fungi in vitro showed that all the compounds exhibited moderate-to-excellent activities. Molecular docking between 8d and the active site of...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yu, Shichong, Chai, Xiaoyun, Wang, Yanwei, Cao, Yongbing, Zhang, Jun, Wu, Qiuye, Zhang, Dazhi, Jiang, Yuanying, Yan, Tianhua, Sun, Qingyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986111/
https://ncbi.nlm.nih.gov/pubmed/24748772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S58680
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky