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Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety
Design and synthesis of triazole library antifungal agents having piperazine side chains, analogues to fluconazole were documented. The synthesis highlighted utilization of the click chemistry on the basis of the active site of the cytochrome P450 14α-demethylase (CYP51). Their structures were chara...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6271785/ https://ncbi.nlm.nih.gov/pubmed/25090121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules190811333 |
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