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Triazole derivatives with improved in vitro antifungal activity over azole drugs

A series of triazole antifungal agents with piperidine side chains was designed and synthesized. The results of antifungal tests against eight human pathogenic fungi in vitro showed that all the compounds exhibited moderate-to-excellent activities. Molecular docking between 8d and the active site of...

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Detalhes bibliográficos
Main Authors: Yu, Shichong, Chai, Xiaoyun, Wang, Yanwei, Cao, Yongbing, Zhang, Jun, Wu, Qiuye, Zhang, Dazhi, Jiang, Yuanying, Yan, Tianhua, Sun, Qingyan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986111/
https://ncbi.nlm.nih.gov/pubmed/24748772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S58680
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