Physical and Functional Interactions of Human DNA Polymerase η with PCNA

Human DNA polymerase η (hPolη) functions in the error-free replication of UV-damaged DNA, and mutations in hPolη cause cancer-prone syndrome, the variant form of xeroderma pigmentosum. However, in spite of its key role in promoting replication through a variety of distorting DNA lesions, the manner...

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Autors principals: Haracska, Lajos, Johnson, Robert E., Unk, Ildiko, Phillips, Barbara, Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99895/
https://ncbi.nlm.nih.gov/pubmed/11585903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7199-7206.2001
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