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Role of p14(ARF) in Replicative and Induced Senescence of Human Fibroblasts

Following a proliferative phase of variable duration, most normal somatic cells enter a growth arrest state known as replicative senescence. In addition to telomere shortening, a variety of environmental insults and signaling imbalances can elicit phenotypes closely resembling senescence. We used p5...

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Detalhes bibliográficos
Main Authors: Wei, Wenyi, Hemmer, Ruth M., Sedivy, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99853/
https://ncbi.nlm.nih.gov/pubmed/11564860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6748-6757.2001
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