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Immortalization of Human Mammary Epithelial Cells Is Associated with Inactivation of the p14(ARF)-p53 Pathway

Inactivation of the ARF-p53 tumor suppressor pathway leads to immortalization of murine fibroblasts. The role of this pathway in immortalization of human epithelial cells is not clear. We analyzed the functionality of the p14(ARF)-p53 pathway in human mammary epithelial cells (MEC) immortalized by h...

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Detalhes bibliográficos
Main Authors: Shamanin, Vladimir A., Androphy, Elliot J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC350550/
https://ncbi.nlm.nih.gov/pubmed/14966292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2144-2152.2004
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