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Immortalization of Human Mammary Epithelial Cells Is Associated with Inactivation of the p14(ARF)-p53 Pathway
Inactivation of the ARF-p53 tumor suppressor pathway leads to immortalization of murine fibroblasts. The role of this pathway in immortalization of human epithelial cells is not clear. We analyzed the functionality of the p14(ARF)-p53 pathway in human mammary epithelial cells (MEC) immortalized by h...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC350550/ https://ncbi.nlm.nih.gov/pubmed/14966292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2144-2152.2004 |
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