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Immortalization of Human Mammary Epithelial Cells Is Associated with Inactivation of the p14(ARF)-p53 Pathway

Inactivation of the ARF-p53 tumor suppressor pathway leads to immortalization of murine fibroblasts. The role of this pathway in immortalization of human epithelial cells is not clear. We analyzed the functionality of the p14(ARF)-p53 pathway in human mammary epithelial cells (MEC) immortalized by h...

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書誌詳細
主要な著者: Shamanin, Vladimir A., Androphy, Elliot J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC350550/
https://ncbi.nlm.nih.gov/pubmed/14966292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.2144-2152.2004
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