Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of apoptosis. This pathway of cell death requires...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2001
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.19.6706-6717.2001 |
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