Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt

Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of apoptosis. This pathway of cell death requires...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Zugasti, Olivier, Rul, Wilfrid, Roux, Pierre, Peyssonnaux, Carole, Eychene, Alain, Franke, Thomas F., Fort, Philippe, Hibner, Urszula
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2001
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.19.6706-6717.2001
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