Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt

Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of apoptosis. This pathway of cell death requires...

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Detaylı Bibliyografya
Asıl Yazarlar: Zugasti, Olivier, Rul, Wilfrid, Roux, Pierre, Peyssonnaux, Carole, Eychene, Alain, Franke, Thomas F., Fort, Philippe, Hibner, Urszula
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Cell Growth and Development
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC99815/
https://ncbi.nlm.nih.gov/pubmed/11533257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6706-6717.2001
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