Molecular Basis for Immunoglobulin M Specificity to Epitopes in Cryptococcus neoformans Polysaccharide That Elicit Protective and Nonprotective Antibodies

The protective efficacy of antibodies (Abs) to Cryptococcus neoformans glucuronoxylomannan (GXM) is dependent on Ab fine specificity. Two clonally related immunoglobulin M monoclonal Abs (MAbs) (12A1 and 13F1) differ in fine specificity and protective efficacy, presumably due to variable (V)-region...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Infect Immun
Päätekijät:	Nakouzi, Antonio, Valadon, Philippe, Nosanchuk, Joshua, Green, Nancy, Casadevall, Arturo
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2001
Aiheet:	Fungal and Parasitic Infections
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3398-3409.2001
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