Molecular Basis for Immunoglobulin M Specificity to Epitopes in Cryptococcus neoformans Polysaccharide That Elicit Protective and Nonprotective Antibodies

The protective efficacy of antibodies (Abs) to Cryptococcus neoformans glucuronoxylomannan (GXM) is dependent on Ab fine specificity. Two clonally related immunoglobulin M monoclonal Abs (MAbs) (12A1 and 13F1) differ in fine specificity and protective efficacy, presumably due to variable (V)-region...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Nakouzi, Antonio, Valadon, Philippe, Nosanchuk, Joshua, Green, Nancy, Casadevall, Arturo
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2001
Pynciau:	Fungal and Parasitic Infections
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3398-3409.2001
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