High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A

Monoclonal antibodies (MAbs) were prepared against the putative binding domain of botulinum neurotoxin A (BoNT/A), a nontoxic 50-kDa fragment. Initially, all fusion products were screened against the holotoxin BoNT/A and against the binding fragment, BoNT/A H(C). Eleven neutralizing hybridomas were...

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Pubblicato in:	Infect Immun
Autori principali:	Pless, Dorothy D., Torres, Edna R., Reinke, Emily K., Bavari, Sina
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.570-574.2001
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