High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A
Monoclonal antibodies (MAbs) were prepared against the putative binding domain of botulinum neurotoxin A (BoNT/A), a nontoxic 50-kDa fragment. Initially, all fusion products were screened against the holotoxin BoNT/A and against the binding fragment, BoNT/A H(C). Eleven neutralizing hybridomas were...
Gespeichert in:
| Veröffentlicht in: | Infect Immun |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.570-574.2001 |
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