pH-Induced Conformational Changes in Clostridium difficile Toxin B

Toxin B from Clostridium difficile is a monoglucosylating toxin that targets substrates within the cytosol of mammalian cells. In this study, we investigated the impact of acidic pH on cytosolic entry and structural changes within toxin B. Bafilomycin A1 was used to block endosomal acidification and...

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Bibliografski detalji

Izdano u:	Infect Immun
Glavni autori:	Qa'Dan, Maen, Spyres, Lea M., Ballard, Jimmy D.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Molecular and Cellular Pathogenesis
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2470-2474.2000
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