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Role of Toxin Functional Domains in Anthrax Pathogenesis

We investigated the role of the functional domains of anthrax toxins during infection. Three proteins produced by Bacillus anthracis, the protective antigen (PA), the lethal factor (LF), and the edema factor (EF), combine in pairs to produce the lethal (PA+LF) and edema (PA+EF) toxins. A genetic str...

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Autors principals: Brossier, Fabien, Weber-Levy, Martine, Mock, Michele, Sirard, Jean-Claude
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97348/
https://ncbi.nlm.nih.gov/pubmed/10722564
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