A Recombinant Carboxy-Terminal Domain of the Protective Antigen of Bacillus anthracis Protects Mice against Anthrax Infection

The immunogenicity and protective efficacy of overlapping regions of the protective antigen (PA) polypeptide, cloned and expressed as glutathione S-transferase fusion proteins, have been assessed. Results show that protection can be attributed to individual domains and imply that it is domain 4 whic...

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Detalhes bibliográficos
Main Authors: Flick-Smith, Helen C., Walker, Nicola J., Gibson, Paula, Bullifent, Helen, Hayward, Sarah, Miller, Julie, Titball, Richard W., Williamson, E. Diane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127760/
https://ncbi.nlm.nih.gov/pubmed/11854261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1653-1656.2002
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