A Recombinant Carboxy-Terminal Domain of the Protective Antigen of Bacillus anthracis Protects Mice against Anthrax Infection

The immunogenicity and protective efficacy of overlapping regions of the protective antigen (PA) polypeptide, cloned and expressed as glutathione S-transferase fusion proteins, have been assessed. Results show that protection can be attributed to individual domains and imply that it is domain 4 whic...

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Autori principali: Flick-Smith, Helen C., Walker, Nicola J., Gibson, Paula, Bullifent, Helen, Hayward, Sarah, Miller, Julie, Titball, Richard W., Williamson, E. Diane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127760/
https://ncbi.nlm.nih.gov/pubmed/11854261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1653-1656.2002
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