Role of Toxin Functional Domains in Anthrax Pathogenesis

We investigated the role of the functional domains of anthrax toxins during infection. Three proteins produced by Bacillus anthracis, the protective antigen (PA), the lethal factor (LF), and the edema factor (EF), combine in pairs to produce the lethal (PA+LF) and edema (PA+EF) toxins. A genetic str...

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Bibliographic Details
Main Authors: Brossier, Fabien, Weber-Levy, Martine, Mock, Michele, Sirard, Jean-Claude
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97348/
https://ncbi.nlm.nih.gov/pubmed/10722564
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