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Role of Toxin Functional Domains in Anthrax Pathogenesis

We investigated the role of the functional domains of anthrax toxins during infection. Three proteins produced by Bacillus anthracis, the protective antigen (PA), the lethal factor (LF), and the edema factor (EF), combine in pairs to produce the lethal (PA+LF) and edema (PA+EF) toxins. A genetic str...

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Detalles Bibliográficos
Main Authors: Brossier, Fabien, Weber-Levy, Martine, Mock, Michele, Sirard, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97348/
https://ncbi.nlm.nih.gov/pubmed/10722564
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