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Role of Toxin Functional Domains in Anthrax Pathogenesis

We investigated the role of the functional domains of anthrax toxins during infection. Three proteins produced by Bacillus anthracis, the protective antigen (PA), the lethal factor (LF), and the edema factor (EF), combine in pairs to produce the lethal (PA+LF) and edema (PA+EF) toxins. A genetic str...

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Détails bibliographiques
Auteurs principaux: Brossier, Fabien, Weber-Levy, Martine, Mock, Michele, Sirard, Jean-Claude
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC97348/
https://ncbi.nlm.nih.gov/pubmed/10722564
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