Differences in the Carboxy-Terminal (Putative Phospholipid Binding) Domains of Clostridium perfringens and Clostridium bifermentans Phospholipases C Influence the Hemolytic and Lethal Properties of These Enzymes

The phospholipases C of C. perfringens (alpha-toxin) and C. bifermentans (Cbp) show >50% amino acid homology but differ in their hemolytic and toxic properties. We report here the purification and characterisation of alpha-toxin and Cbp. The phospholipase C activity of alpha-toxin and Cbp was sim...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jepson, Marie, Howells, Angela, Bullifent, Helen L., Bolgiano, Barbara, Crane, Dennis, Miller, Julie, Holley, Jane, Jayasekera, Pramukh, Titball, Richard W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1999
Pynciau:
Molecular and Cellular Pathogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC116509/
https://ncbi.nlm.nih.gov/pubmed/10377104
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