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Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Production by Human Monocytes Involves the Raf-1/MEK1-MEK2/ERK1-ERK2 Pathway

During gram-negative sepsis, human monocytes are triggered to produce large quantities of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in response to endotoxin (lipopolysaccharide [LPS]). Several studies have identified signal transduction pathways that are activated by LPS,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: van der Bruggen, Tjomme, Nijenhuis, Suzanne, van Raaij, Estia, Verhoef, Jan, Sweder van Asbeck, B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC96660/
https://ncbi.nlm.nih.gov/pubmed/10417144
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