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Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway

Cefotetan is widely used to treat bacterial infections in the clinic owing to its broad spectrum of antibacterial activity. In the present study, we demonstrate that cefotetan can bind to the conserved ligand-binding pocket of human Raf1 kinase inhibitory protein (hRKIP), which acts as a negative re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guo Chenyun, Xu Hao, Zhou Yu, Wu Zhihua, Jiang Bin, Chen Hanyu, Lin Donghai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: China Science Publishing & Media Ltd. 2022-12-01
Saila:Acta Biochimica et Biophysica Sinica
Gaiak:
Sarrera elektronikoa:https://www.sciengine.com/doi/10.3724/abbs.2022188
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