Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation.

Recombinant Mek1 and Raf-1 proteins produced in Sf9 cells undergo a tight association both in vivo and in vitro, which apparently does not depend on additional factors or the kinase activity of Mek1 or Raf-1. The complex can be disrupted by two polyclonal antibodies raised against Raf-1 peptides. Co...

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Xehetasun bibliografikoak

Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Huang, W, Alessandrini, A, Crews, C M, Erikson, R L
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1993
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.10947
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