Proteasome Activity Is Required for Anthrax Lethal Toxin To Kill Macrophages

Anthrax lethal toxin (LeTx), consisting of protective antigen (PA) and lethal factor (LF), rapidly kills primary mouse macrophages and macrophage-like cell lines such as RAW 264.7. LF is translocated by PA into the cytosol of target cells, where it acts as a metalloprotease to cleave mitogen-activat...

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Bibliografske podrobnosti

izdano v:	Infect Immun
Principais autores:	Tang, Guangqing, Leppla, Stephen H.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Molecular and Cellular Pathogenesis
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.3055-3060.1999
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