Proteasome Activity Is Required for Anthrax Lethal Toxin To Kill Macrophages

Anthrax lethal toxin (LeTx), consisting of protective antigen (PA) and lethal factor (LF), rapidly kills primary mouse macrophages and macrophage-like cell lines such as RAW 264.7. LF is translocated by PA into the cytosol of target cells, where it acts as a metalloprotease to cleave mitogen-activat...

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Argitaratua izan da:	Infect Immun
Egile Nagusiak:	Tang, Guangqing, Leppla, Stephen H.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1999
Gaiak:	Molecular and Cellular Pathogenesis
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.3055-3060.1999
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