Proteasome Activity Is Required for Anthrax Lethal Toxin To Kill Macrophages

Anthrax lethal toxin (LeTx), consisting of protective antigen (PA) and lethal factor (LF), rapidly kills primary mouse macrophages and macrophage-like cell lines such as RAW 264.7. LF is translocated by PA into the cytosol of target cells, where it acts as a metalloprotease to cleave mitogen-activat...

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-д хэвлэсэн:	Infect Immun
Үндсэн зохиолчид:	Tang, Guangqing, Leppla, Stephen H.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 1999
Нөхцлүүд:	Molecular and Cellular Pathogenesis
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.3055-3060.1999
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