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Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli
Deletion of topA in Escherichia coli was found to result in a higher level of killing after treatment with either hydrogen peroxide or N-ethylmaleimide. This effect on oxidative challenge response represents a new role for E. coli DNA topoisomerase I in addition to prevention of excessive negative s...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2000
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC94351/ https://ncbi.nlm.nih.gov/pubmed/10633122 |
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