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Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli

Deletion of topA in Escherichia coli was found to result in a higher level of killing after treatment with either hydrogen peroxide or N-ethylmaleimide. This effect on oxidative challenge response represents a new role for E. coli DNA topoisomerase I in addition to prevention of excessive negative s...

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Detaylı Bibliyografya
Yazar: Tse-Dinh, Yuk-Ching
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC94351/
https://ncbi.nlm.nih.gov/pubmed/10633122
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