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Lactococcus lactis as a Cell Factory for High-Level Diacetyl Production

We report the engineering of Lactococcus lactis for the efficient conversion of sugar into diacetyl by combining NADH-oxidase overproduction and α-acetolactate decarboxylase inactivation. Eighty percent of the carbon flux was found to be rerouted via α-acetolactate to the production of diacetyl by p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Appl Environ Microbiol
Prif Awduron: Hugenholtz, Jeroen, Kleerebezem, Michiel, Starrenburg, Marjo, Delcour, Jean, de Vos, Willem, Hols, Pascal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10966436/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.66.9.4112-4114.2000
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