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Cofactor Engineering: a Novel Approach to Metabolic Engineering in Lactococcus lactis by Controlled Expression of NADH Oxidase

NADH oxidase-overproducing Lactococcus lactis strains were constructed by cloning the Streptococcus mutans nox-2 gene, which encodes the H(2)O-forming NADH oxidase, on the plasmid vector pNZ8020 under the control of the L. lactis nisA promoter. This engineered system allowed a nisin-controlled 150-f...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Lopez de Felipe, Felix, Kleerebezem, Michiel, de Vos, Willem M., Hugenholtz, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107362/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9683475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.15.3804-3808.1998
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