Cofactor Engineering: a Novel Approach to Metabolic Engineering in Lactococcus lactis by Controlled Expression of NADH Oxidase

NADH oxidase-overproducing Lactococcus lactis strains were constructed by cloning the Streptococcus mutans nox-2 gene, which encodes the H(2)O-forming NADH oxidase, on the plasmid vector pNZ8020 under the control of the L. lactis nisA promoter. This engineered system allowed a nisin-controlled 150-f...

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Bibliografiske detaljer
Main Authors: Lopez de Felipe, Felix, Kleerebezem, Michiel, de Vos, Willem M., Hugenholtz, Jeroen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Physiology and Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC107362/
https://ncbi.nlm.nih.gov/pubmed/9683475
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