Lactococcus lactis as a Cell Factory for High-Level Diacetyl Production

We report the engineering of Lactococcus lactis for the efficient conversion of sugar into diacetyl by combining NADH-oxidase overproduction and α-acetolactate decarboxylase inactivation. Eighty percent of the carbon flux was found to be rerouted via α-acetolactate to the production of diacetyl by p...

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Main Authors: Hugenholtz, Jeroen, Kleerebezem, Michiel, Starrenburg, Marjo, Delcour, Jean, de Vos, Willem, Hols, Pascal
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Food Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC92266/
https://ncbi.nlm.nih.gov/pubmed/10966436
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