Pharmacokinetic-Pharmacodynamic Modeling of Electroencephalogram Effect of Imipenem in Rats with Acute Renal Failure

The epileptogenic activity of imipenem was investigated in rats with experimental renal failure induced by uranyl nitrate injection by using electroencephalogram (EEG) recording and a pharmacokinetic-pharmacodynamic model including an effect compartment. Results previously obtained with healthy rats...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Antimicrob Agents Chemother
Prif Awduron:	Dupuis, Antoine, Limosin, Anne, Paquereau, Joël, Mimoz, Olivier, Couet, William, Bouquet, Serge
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2001
Pynciau:	Pharmacology
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11709350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.12.3607-3609.2001
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